GM's contract, at a total contract price of US$489.4m, is for 30,000 ventilators to be delivered to the Strategic National Stockpile by the end of August 2020, with a production schedule allowing for the delivery of 6,132 ventilators by 1 June, 2020.
The rating of this contract under the DPA follows President Trump's direction to HHS Secretary Alex Azar to invoke the Defense Production Act with regard to GM's production of ventilators on 27 March.
Azar said in a statement: "Invoking the [act] to secure ventilator production from GM and other companies is a part of President Trump's all-of-America approach to combating the coronavirus.
"By rating contracts under the DPA, HHS is helping manufacturers like GM get the supplies they need to produce ventilators as quickly as possible, while also ensuring that these ventilators are routed through the Strategic National Stockpile to where they're needed most.
"The Trump Administration has deployed thousands of ventilators from the Strategic National Stockpile that have helped save lives in hotspots such as New York so far.
"We're grateful to the GM team for working with the federal government to expand our nation's supply of ventilators as the pandemic evolves."
GM said: "GM and Ventec Life Systems are working with speed and urgency to arm front-line medical professionals with the critical care ventilators they need to treat seriously ill patients.
"GM is proud to deploy its purchasing and manufacturing capability alongside the respiratory care expertise of Ventec.
"We remain dedicated to working with the Administration to ensure American innovation and manufacturing meet the needs of the country during this global pandemic."
GM had said earlier it was training employees at the company's Kokomo plant in the extensive screening, cleaning and other CDC-recommended procedures that would be in place when volume production of Ventec Life Systems' critical care ventilator begins in less than two weeks.
Initial production will begin with one shift, with second and third shifts added soon thereafter.
Each shift will enter and exit through a different door to minimise social contact.